At the recent Televisions Critic's Association press tour, Ostroff revealed that although Smallville is coming to an end after 10 years on the small screen, a replacement should follow soon after: "We have started to talk about if there are other DC comic book adaptations. We haven't picked anything else up to develop yet, but we would like to see something on the air, so we're going to work on it."
Although this is all a little vague, at least it shows that they are planning something! However, she did go on to say that a Smallville spin-off would be a possibility as well but still didnt go into a great amount of detail.
"We are talking about everything," she said when asked whether they'd consider another show featuring any of the Smallville cast. "The characters are there. We're looking at the DC library. There are different parts of the puzzle. At the end of the day, I would love to be able to say that Smallville is going off the air and now we have something else is coming on."