According to Maprincipaute.com, Iron Man 2 will film in Monaco during the Formula 1 Grand Prix circuit and casino. It sounds like it will be mostly Second Unit filming, but you can read a translated version of the article at
Director Jon Favreau's Iron Man 2, opening in theaters on May 7, stars Robert Downey Jr., Gwyneth Paltrow, Don Cheadle, Jon Favreau, Mickey Rourke, Sam Rockwell, Samuel L. Jackson, Scarlett Johansson, Garry Shandling, John Slattery, Kate Mara and Clark Gregg.
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