Writer Kelly Sue DeConnick has announced over her Tumblr page that Avengers Assemble is set to be canceled this March with issue #25.
"[Warren] Ellis wants me to tell you he 'murdered it with special English curse magics,' but in truth the book fulfilled its mandate, so it’s done with issue 25," DeConnick said via tumblr. "Thank you SO MUCH for all the support -- it's been a blast.",
Avengers Assemble launched in 2012 and focused on the cast from "The Avengers" movie, though. The series would evolved over time to feature a number of Avengers from across the Marvel U when DeConnick took over with issue #9.