It's only been a few months since Spider-Island concluded, but Spidey is already gearing up for the next multi-part Amazing Spider-Man story starts in March with issue #682 Ends of the Earth It's the endgame of Doctor Octopus and the Sinister Six's plot against Spider-Man. Dan Slott, who is writing the arc, said "The way it's going to be set structured is going to be very different than Spider-Island."
The next big Spider-Man epic begins in Amazing Spider-Man #682, part one of Ends Of The Earth, by Dan Slott and Stefano Caselli! The Sinister Six, led by the vengeful Doctor Octopus, is back and they’re looking for revenge! Can Spider-Man & Earth’s Mightiest save the world before Doc Ock’s explosive endgame is revealed? Find in Amazing Spider-Man #682 hitting comic shops and the Marvel Comics app this March!