Warning: Spoilers
A make-up artist working on the Spider-Man 3 movie spilled some details about Harry Osborn (played by James Franco) in the upcoming film.
Matthew Mungle's Web site says he "designed and created the make up concept and appliances for James Franco in Spider-Man 3 to be applied by Luisa Abel."
That implies that Osborn will take up his father's Green Goblin gear and possibly become Green Goblin II, becoming the third villain along with the Sandman and possibly Venom in battling Spidey. In the comics, Harry did become Green Goblin II and fought the Hobgoblin, eventually dying to save his friend Peter Parker.
But a studio insider told IESB: "Rob, all the assumptions that Harry Osborn is the third villain the Hobgoblin are all wrong. Spiderman finds himself out numbered in this one. When everything seems to be at its worst for our hero, he finds himself an unlikely ally, Harry Osborn. Peter Parker's best friend will come to his aide."
Also, "We will see Harry battling his inner demons to make the choice between his father's legacy and his best friend. I will fill you in more later but gotta go, crew call in 10 minutes, Sam doesn't like it when anyone's late!"