From what we know we can name a few things. First, Batman has been away for a while. Jim Gordon has been named a war hero. Bane has surfaced somewhere in Gotham. And that Selena Kyle is involved. Now Lets piece it together. Batman, we know is on the run because of what happedened in TDK, is called back into action after bane attacks some place in Gotham City. An attack which I think puts Jim Gordon in the hostpital, and he needs someone to run things while hes away, which is where Joseph Gordon-Levitt's character comes in.
Bane, we know recieves some sort of blood tranfusion or something like that, I think he does take some sort of venom like the books, but needs a regular blood tranfusion because his blood is poisoned from the toxins. Now, Selena Kyle I think reaches out to Bane with some secrets or something of value to him. As for Marion Cotillard's character I do not think that she will be Talia Al Ghul, only because there is still Joey Kings character which might not make a whole lot of sense now, but I think she will play a younger Talia Al Ghul.
Those are my thoughts Comment below if you think differently.