Ralph Fiennes as Doctor Doom/Dr. Victor von Doom
Eric as Mr. Fantastic/Dr. Reed Richards
Naomi Watts as Invisible Woman/Susan Storm-Richards
Dane DeHaan as the Human Torch/Johnny Storm
Mark Whalberg as The Thing/Ben Grimm
Danny DeVito as Mole Man/Harvey Rupert Elder
Alice Braga as Alicia Masters
NOTABLE CAMEOS:
Samuel L. Jackson as Nick Fury, Director of SHIELD
Stan Lee