Marvel Universe:
Sam Worthington as Captain America/Steve Rogers
Mark Vally as Captain America/Steve Rogers
Chris Hemsworth as Thor
Alexander Skarsgard as Thor
Ioan Gruffudd as Mister Fantastic/Reed Richards (Sequel)
Justin Bartha as Mister Fantastic/Reed Richards (Reboot)
Jessica Alba as The Invisible Woman/Susan Storm (Sequel)
Diane Krueger as The Invisible Woman/Susan Storm (Reboot)
Chris Evans as the Human Torch/Johnny Storm (Sequel)
Paul Walker as the Human Torch/Johnny Storm (Reboot)
Michael Chiklis as The Thing/Benjamin Grimm (Sequel or Reboot)
Julian Mcmahon as Dr. Doom/Victor Von Doom(Sequel)
Mark Strong as Dr. Doom/Victor Von Doom(Reboot)
Wentworth Miller as Galactus (Reboot)
Doug Jones as The Silver Surfer (CGI)/Laurence Fishburne (Voice)
Mark Wahlberg as Daredevil/Matt Murdock (Reboot)
Jordana Brewster as Elektra (Reboot)
Michael Clarke Duncan as Kingpin (Reboot)
Timothy Olyphant as Bullseye (Reboot)
Hugh Laurie as Ben Urich (Reboot)
Robert Downey Jr as Iron Man/Tony Stark
Don Cheadle as War Machine
Scarlett Johansson as Black Widow
Tobey Maguire as Spider-Man/Peter Parker (Sequel)
Emile Hirsch as Spider-Man/Peter Parker (Reboot)
Thomas Dekker as Spider-Man/Peter Parker (Reboot)
Mary Elizabeth Winstead as Mary Jane (Sequel or Reboot)
Cam Gigandet as Flash Thompson (Reboot)
Bryce Dallas Howard as Gwen Stacy (Sequel)
Isabel Lucas as Gwen Stacy (Reboot)
Willem Dafoe as Green Goblin/Norman Osborn (Sequel or Reboot)
Ralph Fiennes as Green Goblin/Norman Osborn (Reboot)
Hugo Weaving as Green Goblin/Norman Osborn (Reboot)
Alfred Molina as Doc Oc (Sequel)
Dominic Purcell as Venom
Thomas Haden Church as Sandman (Sequel)
J.K Simmons as J. Jonah Jameson (Sequel or Reboot)
Patrick Stewart as Professor X (Sequel or First Class)
Ian Mckellen as Magneto (Sequel)
Clive Owen as Magneto
Hugh Jackman as Wolverine (Sequel)
Lieve Schrieber as Sabretooth (Sequel)
Ryan Reynolds as Dead Pool
Ray Wise as William Stryker
Christopher Pine as Cyclops/Scott Summers (First Class)
James Marsden as Cyclops/Scott Summers (Sequel)
Famke Janssen as Jean Grey (Sequel)
Halle Berry as Storm (Sequel)
Naomie Harris as Storm
Kelsey Grammer as Beast (Sequel)
Taylor Kitsch as Gambit
Josh Holloway as Gambit
Kirstin Stewart as Jean Grey (First Class)
Anna Paquin as Rouge (Sequel or First Class)
Shawn Ashmore as Ice-Man (Sequel or First Class)
Ellen Page as Kitty Pryde (Sequel or First Class)
Daniel Cudmore as Colossus (Sequel or First Class)
Kristin Kreuk as Jubilee
Thomas Jane as The Punisher (Sequel)
Nicolas Cage as Ghost Rider/Johnny Blaze (Sequel)
Edward Norton as The Hulk/Bruce Banner