Reed Richards/Mr.Fantastic-Karl Urban(pathfinder,chronicles of riddick,star trek) i think he has the right look
Sue Storm/invisible woman-Julie Benz(rambo,boondock saints 2,punisher warzone)
Johnny Storm/Human Torch- Jared Padelecki(supernatural, friday the 13th)
Ben Grimm/The Thing-enrico colantoni (veronica mars)
Dr. Doom- Jason Isaacs (patriot, peter pan, harry potter)
Alicia Masters-Laura Ramsey (ruins,the covenant)