Anton Yelchin as Peter Parker/Spider-Man
Yeah, I know he's the fan favorite for Harry's role but I think he can pull off a decent Peter Parker, but just remember this is my vision of Spider-Man, and heck, I saw Fright Night on Friday, and he's sold me that he can play Peter Parker.
Sasha Pieterse as Gwen Stacy
After watching Geek Charming last night, (yes yes I know *sigh*) And she is everything I want Gwen to be, pretty, smart, laid-back, and easy going, plus I think I have a teeny weeny crush on her. :D
Rosemary Harris as Aunt May
There is no denying that she is Aunt May, I watched Spider-Man 2 last night, and I still can't believe how good she is in the Spider-Man films.
Ralph Fiennes as Norman Osborn/The Green Goblin
Have you seen the Harry Potter films? He's like really [frick]ing evil, and the beginning of HP: DEATHLY HALLOWS PT1? I think he's a good enough actor to play this crazy [frick].
Denis Leary as Captain Stacy
[frick] IT.
You guessed it....
J.K Simmons as Triple J
TA-DA!! TRIPLE J! I REALLY HOPE THEY CAN BRING HIM BACK FOR THE REBOOT, HE IS, TOTALLY NON-REPLACEABLE!!