Spider-Man has arguably the best rogues gallery in comicbook history but.. certain villains are just meant and aren't meant to be on the big screen. I'll be mentioning the following that are meant to be and yes that includes previous and upcoming Spider-Man film villains.
Let's start off with my favorite... The Lizard!
Cinematically both visually and emotionally this character has so much potential. Here is my reasons why he is meant to be a big screen Spider-Man villain. 1: His backstory is great and his motivations are to be admired. A former army surgeon caught in a fire fight and his arm gets amputated in a fight and he becomes a biologist and is fascinated by how some reptiles can regrow missing limbs then tests it on a rabbit then himself but unfortunately it has side effects on him. 2: Now visually it's pretty clear why he would be great to see in a Spidey film but emotionally goes deeper. He is Spider-Man's greatest ally but one of his deadliest enemies, his relationship with his wife is Rocky because of his alter-ego and at one point in the comics The Lizard eats and kills Connors son. There is so much opportunity emotionally for this character and it's hard to ignore it.
Mysterio
He is meant to be because as I've stated in my article "Spider-Man villains that would make for a great movie." He more than likely would be better with another villain to compliment hin on screen but he would be a great villain mentally. Alot of villains you see in movies are challenging physically but Mysterio would make for a great mental villain if done right.
Fan Favorite... Venom!
Now everyone has made it clear and it was obvious that Venom was misused in Spider-Man 3 all though I think they portrayed the Eddie Brock character. Anyways he is meant to be because of the challenge he creates for Spider-Man and he is like Lizard he is visually something to see on the big screen.
Carnage
Can't have Venom without Carnage, am I not right? Carange is meant to be because Venom is the reason Carange even exsits but Carnage poses as a threat to both the wall crawler and Venom.
Green Goblin
We've seen him before in the original Spider-Man and the suit got mix to negative reactions. He deserved to be on the big screen for a reason, he is Spider-Man's arch-nemesis. He is tied with Venom, Carnage and Doc Ock as Spidey's greatest enemy. He is the mental threat as well as the physical threat that Spider-Man needs.
Speak of the devil.... Doc Ock
Well I'll be honest I don't know why I listed Doc Ock when he was brought to perfection in Spider-Man 2.
What are your thoughts? Leave comments and be respectful