The Lizard would be the perfect villain for the fourth Spidey film, says Spider-Man 3 producer Grant Curtis, talking with iF Magazine.
"For me it's hard to beat the Lizard, it truly is," he said. "That's just me talking. I think the Lizard has got a great story of not only personal pain but also emotional pain, and trying to mask both of those, it's a strong storyline. The Lizard has always been a favorite of mine, even before working on these movies. I've always liked Kraven The Hunter, but he'd have to be used selectively. For me though it would have to be the Lizard."
Dylan Baker has appeared as Dr. Curt Conners (who becomes the Lizard after experimenting with regeneration) in the last two Spider-Man films.