The character (played by Elizabeth Banks) didnt really have too much screentime in the last three movies, but according to Showbiz Spy, a "movie insider" has told them that she'll have a much larger role and that Marc Webb already has an actress in mind for who should play her!
"Betty was a minor character in the previous Spidey movies but Marc has big plans for her. He wants a strong performer to carry the role and Zooey fits the bill perfectly. The role is hers if she wants it."
It's worth remembering that Betty Brant was Peter Parker's first love interest for a little while back in the 1960's, so could that be the big plans that Marc Webb has for the actress? Although I'm hoping to see Gwen in that role, Deschanel is a fantastic actress and seems like a great choice, so here's hoping it works out!
Oh, and in a slightly pointless bit of trivia for you, Zooey's sister (Emily, star of TV series
Bones) was actually in
Spider-Man 2 as the receptionist Peter delivers pizzas to at the start of the movie. You learn something new every day, huh? :)
The currently untitled
Spider-Man movie is set to be released in 3D on July 3, 2012!