Let me get this out of the way, I have very little knowledge of Doctor Strange. I know the basic concept and the Marvel Studios is keen on the idea of giving the titular character a solo film. Based on pure acting talent and looks, I believe Jean Dujardin would make a great Sorcerer Supreme.
Jean Dujardin
AGE: 39
Notable Roles:
OSS 117: Cairo, Nest of Spies,
The Artist
Awards: César Award for Best Actor (2007 nominee), Cannes Film Festival Best Actor Award (2011 winner), Golden Globe Best Actor - Musical or Comedy (2012 winner), Academy Award for Best Actor (2012 pending)
Reasoning: Dujardin is a great acting talent. He is still unknown to the general public which allows the audience to believe that he is in fact the Sorcerer Supreme (think Christopher Reeve as Superman). Also, it will allow Disney/Marvel extra budget not reserved for cast. Most importantly, Jean Dujardin is an excellent actor and can play Doctor Strange perfectly.