UPDATE: SUPERNATURAL Season 10, Episode 3 Promo; "Soul Survivor"
The relationship between the Winchester brothers is being pushed to the limit thanks to the influence that the Mark of Cain is having on Dean, and in this first look at next week's episode
"Soul Survivor" - Sam (Jared Padalecki) continues his efforts to save Dean (Jensen Ackles) from the Mark of Cain. Crowley (Mark Sheppard) realizes Dean’s demonic antics are starting to cause problems for him in Hell so he searches out an unlikely ally – Castiel (Misha Collins). Jensen Ackles directed the episode written by Brad Buckner & Eugenie Ross-Leming (#1001).