Ian Somerhalder as Peter Parker/Spider-Man
I think Ian Somerhalder is awesome in Vampire Diaries & Lost and I don't think just cos someone looks like Peter Parker they should be Spidey but you've gotta be a good actor, luckily this guy has both ;)
Christian Serratos as Maryjane Watson
I think she has what it takes to be MJ plus she's hotter than Kirsten Dunst...
Meryl Streep as Aunt May
Too me it's pretty obvious why...
Mel Gibson as J. Jonah Jameson
I think Mel's an awesome actor, as a Scotsman watching Braveheart it still brings a tear to my eye watching his awesome acting on an old Scottish hero, and he has good comical sence so he could also play JJ!
Christopher Meloni as Norman Osborn
I've only seen him in Law & Order but I think he was very like Stormin Norman :P
Anton Yelchin as Harry Osborn
I'm a huge fan of the new Star Trek movie and I really enjoyed Yelchin's performance.
Matthew Goode as Quentin Beck/Mysterio
I LOVED the Watchmen and Ozymandias and he just really reminded me of Mysterio right down to the way he talks.
Dominic Purcell as Eddie Brock/Venom
Do I have to explain this one ? ;)
Mark Pellegreno as Cletus Cassady/Carnage
I'm a LOST & Supernatural fanatic and think that going from Lucifer to Carnage would be easy for him.
Jackie Earl Haley as Chameleon
I always see him as a masked madman so it would be easy for him...
Stephen Lang as Tombstone
I think he suits the role of Tombstone more than JJ..
Michael Clarke Duncan as Kingpin
He's a great actor plus the fact he did two great performances in two of my favourite films (Armageddon & The Green Mile)....
What're you talkin about I'm not biased... shut up ;)
I'm really busy cos I've got exams just now so i'll update it later with the rest of my cast..