Andrew Garfield as Peter Parker/Spider-Man
While recovering from Gwen's death by Harry's actions from Amazing Spider-Man 2, Peter will try to manage a virgin to ensure that nobody else dies because of him just before he meets Black Cat and Mary Jane.
Felicity Jones as Felicia Hardy/Black Cat
Formerly an assistant to Norman and Harry Osborn, Felicia Hardy will be expected to become Black Cat at some point in this film and Felicity Jones will be intended on reprising her roles for sure since she mentioned what her character is about to go through and as the film's female lead, she will be the girl to help Spider-Man get over his worries and try to start new once he starts his relationship with MJ.
Guy Pearce as Kraven the Hunter
As the villain director Marc Webb wants as the main antagonist of the film, Kraven the Hunter is one of the potential Spider-Man villains planned for the Sinister Six film. Even though it doesn't look like he would fit in the film, there are way's Kraven can be improved. While doing so, Kraven should have an army of mercenaries working for him on capturing Spider-Man.
Shailene Woodley as Mary Jane Watson
Peter Parker's new girlfriend.
Sally Fields as Aunt May
Peter's overprotective aunt
Zoe Saldana as Calypso
Kraven's love interest and with Zoe hooking up more with plain American actors than african American actors in films, she does look good for the role of Calypso
Michael Massee as Gustav Fiers
Paul Giamatti as the Rhino
Other Rumored Cast Members
Dane Dehann as Harry Osborn
Peter's best friend who betrayed him by mudering Gwen Stacy in Amazing Spider-Man 2
Nathan Fillion as the Scorpion
That is all.