One year after the attack of The Joker, new villains emerge in Gotham City, among them a new mobster and the terrible Ice Killer. So the city needs the help of the Dark Knight, which fights against the task-force created with the help of Oswald Cobblepot and the businessman Roman Sionis. Bruce Wayne meets the woman who saved his life, Dr. Leslie Thompkins, that returns at Gotham City together of the socialite Talia Head.
Christian Bale as Batman/ Buce Wayne
Michael Caine as Alfred Pennyworth
Gary Oldman as Commissioner Jim Gordon
Morgan Freeman as Lucius Fox
Bob Hoskins as The Penguin / Oswald Cobblepot → The new mobster in the city. However nobody knows his double identity.
Christoph Waltz as Roman Sionis / Black Mask → The owner of Janus Cosmetics Corporation, and loves masks. Becomes insane after his company was sold to Bruce Wayne. So he becomes the mobster known as Black Mask, a rival of The Penguin, the Batman and Bruce Wayne.
Marion Cottilard as Talia Head → A mysterious socialite. She came from France alongside the Dr. Leslie Thompkins. She becomes friend of Bruce Wayne.
Tom Hardy as Mr. Freeze → Victor Fries was a inmate of the Arkham and suffers from a genetic disorder that compels him to live at temperatures below the ice. Also known as Killer Frost because he freeze his victims. He was hired by Penguin to ends with rival mob and Batman.
Cillian Murphy as Scarecrow/ Dr. J. Crane → Hired by Black Mask to ends Batman, Bruce Wayne and The Penguin.
Tim Booth as Victor Szasz → Hired by The Penguin.
Allison Janney as Dr. Leslie Thompkins → A doctor and close confidant of Bruce Wayne and Alfred. She helped Alfred after the death of the Bruce' parents. She returned to Gotham City alongside of new friend, Talia head that she met in Paris.
Oliver Platt as Detective Harvey Bullock → The new detective in GCPD. He is a member of task-force against Batman, so he belives that batman is a enemy. His partner discusses with him about Batman. Bullock is a cinephile and likes doughnut. Bullock is the Wuertz's substitute in GCPD.
Zuleikha Robinson as Renée Montoya → She substitutes Ramirez in GCPD and becomes Bullock's partner and member of task-force against Batman, however, she belives in his innocence.