Let’s get on with it.
RAIDEN
A rookie from the supposedly re-established FOXHOUND, Raiden is called in to eliminate a terrorist threat from an offshore decontamination facility and rescue the president. In time, he realizes that there is much more to this mission than what he's being told, and will have to make a hard choice that may put many lives in jeopardy.
Who Should Play Him: Chace Crawford
WHY: He might be a young, pretty-boy actor who has a lead role in the “rich teens with silly problems” show Gossip Girl, but Chace is definitely one of the more talented actors in that series, and actually has way more potential than most of his peers in acting. Plus he does sound quite a bit like Quinton Flynn.
ROSEMARY
Raiden's live-in girlfriend, who is a data analyst and determined to make him more open with her. There may be more to her than it seems though…
Who Should Play Her: Olivia Wilde
WHY: Olivia is not only beautiful, but she’s also intelligent and one of the few “sex symbol“ actresses who actually can act. She has a great resemblance to Rose as well, so she can definitely bring out the conflicted nature of Rose’s personality and look good to the fan boys while doing it.
VAMP
A Romanian with a penchant for knives and a taste for blood, Vamp is a tough cookie, being apparently immortal. He was once involved with Commander Scott Dolph before later becoming close with Dolph's daughter Helena/Fortune.
Who Should Play Him: Olivier Martinez
WHY: He's got the dark good European looks and the physique required for this part. Just tweak his voice and give him Vamp's signature dance-battle style and knives, and we're more than set.
SOLIDUS SNAKE
In the first Metal Gear Solid Solidus shows up in the post-credits at the end of the game in the role of U.S. President George Sears, and is a major character in the second game. He's the third of Big Boss' clones, an agent of the Patriots, and Raiden's adopted father. He is forced to resign from office after his involvement with Metal Gear REX and the Genome Project soldiers becomes public, as he'd before advocated against genetic engineering, and becomes a terrorist with the group The Sons of Liberty.
Who Should Play Him: Jeff Bridges
WHY: Well, Solidus looks exactly like Big Boss, but not exactly. He is also very different in terms of his personality, as well as pretty physically fit. Jeff Bridges played a great villain in Iron Man, and he certainly can pull off being over-the-top.
OLGA GURLUKOVICH
A Russian mercenary whom Snake first encounters aboard the Tanker, Olga is a tough cookie. She has been raised all her life to be strong, both out of necessity and because her father was a colonel for a Russian private army. She is seen again in the Plant, having inherited her father's unit after the old man died. She may or may not be having her own agenda.
Who Should Play Her: Kate Nauta
WHY: Kate Nauta, best known for her role as the assassin from Transporter 2, is not a really huge star, and Olga doesn’t have much screen time for all her importance in the story. It also helps that she just looks natural as a ruthlessly tough soldier girl.
FORTUNE
Fortune, real name Helena Dolph-Jackson, was born a perfectly normal girl in a perfectly normal family with her mother and her Marine commandant father, Scott, and then later married a man known as Colonel Jackson. Her life took a shocking swerve when her father unexpectedly died, which was followed by her husband being jailed for a crime he didn’t commit, leading to her mother to kill herself, and it was all topped off with Helena miscarrying her child; essentially, she lost her whole family in the span of a few months. She joined the military, and found out she had impossibly good luck on the battlefield, quickly earning herself a place as a leader in her late husband’s unit Dead Cell.
Who Should Play Her: Gina Torres
WHY: Yeah, obligatory Firefly/Serenity alum here. But seriously, Gina Torres is pretty much perfect for Fortune, who is both strong, but also very vulnerable thanks to the numerous tragedies in her life. After all, what more could you ask for? She’s tall and athletic, and is actually a good actress.
FATMAN
The mad bomber of Dead Cell, Fatman is obsessed with his handiwork. His codename refers not to his girth, but to the atomic bomb that destroyed Nagasaki. He is obsessed with becoming a legend among bombers and wishes to go out in a grand fashion, just like his explosives.
Who Should Play Him: Paul Giamatti
WHY: Why not? He’s just a great actor, has the build, and just does great playing crazy.
EMMA “E.E.” EMMERICH
The younger stepsister of Hal Emmerich, Emma clearly takes after her brother in her expertise in technology. Ever since an accident claimed the life of her stepfather and left her horribly injured, Emma became resentful of Hal because she felt he abandoned her and her mother when they needed his help. She strives to surpass her brother by becoming a genius hacker.
Who Should Play Her: Ellen Page
WHY: Well, she’s young, cute and sassy. What more is there to say?
OTHER CHARACTERS
For the smaller characters who only appear in a couple scenes, get small time actors. Admittedly, I’d love to get Jack Coleman to play Richard Ames.