Matthew Fox as Commander Shepard
Doug Jones as Garrus Vakarian
Amanda Seyfried as Tali’Zorah nar Rayya
Yvonne Strahovski as Miranda Lawson
Laz Alonso as Jacob Taylor
Steve Buscemi as Mordin Solus
Willem Dafoe as Thane Krios
Noomi Rapace as Jack/Subject Zero
Jason Momoa as Grunt
Diane Lane as Samara
D.C. Douglas as the voice of Legion
Kelly Hu as Kasumi
Temuera Morrison as Zaeed Massani
Seth Green as Jeff "Joker" Moreau
Tricia Helfer as the voice of EDI
Larissa Oleynik as Kelly Chamber
Meryl Streep as Doctor Chakwas
Martin Sheen as Illusive Man
Well, that is everyone. Let's hope that Mass Effect 3 will be just as awesome with more great fancast opportunities.