Channing Tatum as Eddie Brock/Venom
Instead of a skinny version of the ultimate Spider-man villain, how about a big, handsome Peter Parker Opposite. Channing is a little old to be a high school character (30 years old), but maybe after graduation Brock and Parker could meet.
Isaach de Bankolé as Killer Croc
Ever since Casino Royale, I have been attracted to this casting idea. He has the large build and machete skills to play the psychotic serial killer, and is a good actor.
Jake Abel as William Hand/Black Hand
Pre-Black hand as a rich inventor would be perfect for Abel. Then, after the transformation would be the battle for him, as he would have to build himself for the role. I can see how it can go wrong, but I can also see it going terribly right.
Ben Mendelsohn as Norman Osborn/Green Goblin
Mendelsohn has shown he can play corrupt and greedy business men in The Dark Knight Rises as a minor villain. Let’s see if he can handle the same type of character (without suit) in a main role. I am intrigued as to how this can go.
Jason Issacs as Ra's al Ghul
A fan favorite to play the sword swinging immortal foe of The Dark Knight, Jason Issacs is no stranger to villains (Lucius Malfoy and Captain Hook). This is a big role to fill, especially with Liam Neeson as a predecessor.
Sorry about the lack of pics, my computer isn't letting me upload them. But let me know what you think of my decisions and let me know your own suggestions for villains you want to see.