Ewan McGregor as Mister Fantastic
I was really stuck on this one, and was just considering recasting Ioan Gruffud because of how perfect he was. Then I came across ewan McGregor, and the more I thought about it, the more I fell in love with it.
Alice Eve as Invisible Woman
Alice Eve certainly looks the part, and I reckon she'd do a pretty great job as a kickass female superhero.
Andrew Garfield as Human Torch
As we've seen in the Amazing Spider-Man films, Andrew Garfield is great at playing a fun comic book character. I know a lot of people didn't like those films, but I thought he did a fantastic job as Spider-Man and brought a lot of life to the films, and I feel like he'd do the same here.
Nathan Fillion as Thing
Nathan Fillion is a fun actor, and he'd bring a great personality to Thing.
Michael Fassbender as Doctor Doom
Michael Fassbender would bring his intimidating and chaotic acting skills to make the perfect Doctor Doom that we've been waiting for. Doom wouldn't be a one-off villain, as I think he'd be perfect to become the next Loki-type character, and be used across several films in the MCU, and maybe, eventually join the side of the heroes.
Zachary Quinto as Silver Surfer
After his fantastic performance as Spock, I feel like he'd nail this role.