Wow!
The New 52 will see a new Cyborg Superman, no longer the human Hank Henshaw, but actually the father of Kara Zor-El!
That means the new Cyborg Superman is actually Supergirl's father!
Michael Alan Nelson said the following:
And the biggest difference in the New-52 character, and one that I hope is common knowledge by the time this comes out, is that Cyborg Superman is no longer Hank Henshaw. He's actually Zor-El, Kara's father. Readers will have to wait until they read the Villains Month issue to learn just how he became Cyborg Superman, but that is the single biggest difference between the new and pre-52 character.