According to the site Bleeding Cool by Rich Johnston, he was hanging out at New York Comic Con and has the scoop one which characters we can expect to see in the upcoming Deadpool movie...
"Of course, some of the characters are very closely associated with Deadpool anyway. There’s Blind Al, Deadpool’s sort-of-roommate, and Patch, the barman-come-mercenary dispatcher who gives Deadpool his jobs. I’m sure you were already expecting those. Then there’s several Weapon-X characters, including (but not limited to) Wyre, Ajax, Sluggo and Garrison Kane.
Wade Wilson’s love affair with Vanessa Carlysle is apparently a key part of the story, though I’ve been promised that she’s never seen in her Copycat guise and there’s no indication she’s a mutant at all. But this won’t be a mutant-shy production…"
Of course there is also another character that we have already seen in a couple of X-Men movies, set to make an appearance. Can you guess which one it is???
It is Colossus. Rich asked whether he would be making a cameo with just one scene and the response was...
"Nope. He is in more than one scene and has got some stuff to do."
Now the question is, will the original Colossus Daniel Cudmore be asked to reprise his role? I guess we will have to wait and see...