With the apocalypse avoided and season 5 ended, many fans had the same question, "Where will they go from here?" The worries are valid because many fans have the same fear which is after the apocalypse the show will just fizzle out and will have extended it's stay.
Well in an interview with a Brazilian magazine Jensen Ackles hints as to where they will go with the sixth season.
"For the creative aspect, we need to understand we just got over a gigantic climax and we’re getting into an unknown territory. The Apocalypse was avoided. That’s why we are going forward a few years and see where the Winchesters are and how it’s their lives. I can’t help, but think of the final scene of “The Hurt Locker” (2009 Oscar winner), when the main character sees himself in front of a shelf with several cereal boxes and doesn’t know what to do. The guy disarms bombs in Iraq, but gets lost on the supermarket! That is not his reality, just like not being a hunter looks like a different world to Dean. All his life was dedicated to one single task, almost like a voluntary slavery, now it’s time to face the monster of real world. That’s totally new to me, through the acting perspective, and I’ll explore a lot more of Dean’s life, that’s why I’m so excited. A kind of introspective tension, like inside monsters."
So what are some of the fans thoughts about the direction they're taking? Do you think it sounds interesting or maybe like they might be trailing away from the whole "Supernatural" aspect of the show. I won't jump the gun on this. I think it would be interesting to see Dean settle into a normal life, because I feel he couldn't cope with it. It would be too boring for him after awhile, but I hope they eventually get the brothers back on the road hunting urban legends and that, of course, Misha Collins comes back.
If you would like to read the entire article the source is below. It's a girl's translation of the Brazilian article. Jensen talks about directing a future episode and his thoughts on the mythos of the show.
http://ditta-spn.livejournal.com/18365.html