Lets also consider this. What other superhero fights vampires? Blade of course. You have Blade coming to New York to hunt this new vampire and also Spider-man who is trying to figure out who's been draining peoples blood in New York.
You'd have Tobey Maguire as Spider-man/Peter Parker and Wesley Snipes as Blade (When he get's out of jail). I think this would be a very smart move by Marvel and I know Mr. Raimi would do it because he's a smart guy.
I guess all we can do is cross our fingers and hope.