This from Worstpreviews.com:
"I don't want to keep repeating myself and just doing films about war," he said at the Venice Film Festival. "This is a very psychological film about sophisticated man fighting primitive man."
He continued: "It's actually possible today, with all the cloning and stem cell research, to actually have some experiments that don't work very well and get out of control."
Rambo 5 will be kick ass if it is anything like Rambo 4. That movie was cut throat awesome. I want to see Sly slitting throats and shooting people or hybrid humans (I don't really care which) in the face with a compound bow from short range. Bring it ON!!!