Zach Cregger's RESIDENT EVIL Reboot Reportedly Eyeing ANORA Star Mikey Madison For Female Lead

Zach Cregger's RESIDENT EVIL Reboot Reportedly Eyeing ANORA Star Mikey Madison For Female Lead

Mikey Madison, who won Best Actress at this year's Oscars for her titular role in Anora, has reportedly been offered the female lead in Sony's Resident Evil revival.

By MarkJulian - Mar 29, 2025 06:03 PM EST
Filed Under: Video Games
Source: SFFGazette.com

Fans of Capcom's renowned survival horror video game were ecstatic to recently learn that Sony was contemplating a reboot of the original Resident Evil film series, which starred Mila Jovovich.

Compared to the Jovovich/Paul W. S. Anderson-developed films, which included a number of original characters and story twists, the reboot is said to be far more true to the storyline of the Capcom video game franchise.

Recently, Austin Abrams (Euphoria) was offered the role of the male lead in the reboot, which is written and directed by Zach Cregger (Barbarian, Companion).

Now, a new report from World of Reel states that Anora award-winning actress Mikey Madison is now in talks for the female lead.

The unconfirmed plot of the film is said to center on, "a hapless courier (Abrams) tasked with delivering a package to a remote hospital. He finds himself caught in the middle of an outbreak and must fight through hordes of mutated creatures to survive."

While the story line of the reboot is believed to be much more similar to that of the Capcom games, the setting does not sound like Spencer Mansion or Raccoon City, where the first two original Resident Evil games take place.

Following the $1.28 billion worldwide gross of six installments of the Anderson/Jovovich film series, Sony has spent the last few years grappling with finding a viable creative formula for the franchise's continuation.

Kaya Scodelario (Skins, The Gentlemen), Hannah John-Kamen ( Ant-Man and the Wasp, Thunderbolts*), Robbie Amell (Code 8, The Flash) led a 2021 film reboot, titled Resident Evil: Welcome to Raccoon City, which grossed $42 million worldwide off a production budget of $25 million.

The film was also a critical failure, nixing any plans for a potential sequel.

Sony and Capcom then pivoted to Netflix with an 8-episode, live-action television series released in July 2022. It starred the late Lance Reddick as a clone of Albert Wesker, in an original story that contained elements of the video game series' storyline.

The upcoming Resident Evil reboot is currently set for release on  Sept. 18, 2026.  Shay Hatten (John Wick: Chapter 3 – Parabellum, Army of the Dead) is co-writing alongside Cregger.

Given the anticipated influx of opportunities following Madison's awards run, it's worth noting she may not accept this role.

Stay tuned for further updates on the reboot, as the current release date for the film indicates that cameras will likely begin rolling shortly.

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harryba11zack
harryba11zack - 3/29/2025, 3:16 PM
it won't top this
Urubrodi
Urubrodi - 3/29/2025, 3:20 PM
Why is it so hard to adapt the games? One movie per game. It's not that complicated.
bkmeijer1
bkmeijer1 - 3/30/2025, 5:12 AM
@Urubrodi - I honestly prefer the premise in this article to that. We've seen the Raccoon City story so many times in different media already, I think it's better to try something new. Preferably set within the games' universe
Urubrodi
Urubrodi - 3/30/2025, 6:32 PM
@bkmeijer1 - The thing though is that whenever they try "something new" with Resident Evil in live-action it goes horribly wrong. To me they should play safe.
bkmeijer1
bkmeijer1 - 3/31/2025, 2:14 AM
@Urubrodi - true, the Netflix show was abysmal. I think they tried every path with adapating it, so maybe they should just leave it altogether.
Urubrodi
Urubrodi - 3/31/2025, 6:12 AM
@bkmeijer1 - Yeah, or that. I rather Capcom just focused on the games, they have been on a row since 7, especially with the remakes.
bkmeijer1
bkmeijer1 - 3/31/2025, 11:16 AM
@Urubrodi - the game remakes are probably the reason I don't need to see them adapted in live-action. Really we'll get Zero and Code Veronica remakes as well
Repian
Repian - 3/29/2025, 3:23 PM
She could play a great Ada Wong.
User Comment Image
Humperdink
Humperdink - 3/29/2025, 3:28 PM
@Repian - I see it in that pic but it's so interesting how most people think she's Asian when she's actually of eastern European Jewish ancestry.
dagenspear
dagenspear - 3/29/2025, 8:27 PM
@Repian - I've seen nothing that says the actress is asian.
Lisa89
Lisa89 - 3/29/2025, 3:26 PM
@MarkJulian - Why not use an image of Mikey Madison for the thumbnail?
DTor91
DTor91 - 3/29/2025, 8:01 PM
@Lisa89 - Or an actual RE image.

I can’t tell if this is AI or not either, but considering @MarkJulian ‘s past bullshit, wouldn’t put it past him.

Making an RE article, one that’s a couple of days late at that, and couldn’t even be bothered to respect it. The pay can’t be that great.
TheFinestSmack
TheFinestSmack - 3/29/2025, 8:07 PM
@Lisa89 - I was gonna say, I don't really know much about this lady but I did not think that was her in the pic.
TrentCrimm
TrentCrimm - 3/30/2025, 7:38 AM
@DTor91 -

Reverse image search brings back nothing except results for this article, and a random russian article repeating the same information, so I'm betting it's something he threw together for this article with AI.
DTor91
DTor91 - 3/30/2025, 5:37 PM
@TrentCrimm - Yup, did a reverse image search as well, and got the same exact thing.
Gabimaru
Gabimaru - 3/29/2025, 6:33 PM
Lol i was confused at the thumbnail. I thought to myself that girl does more look like the daughter of selene in underworld
Repian
Repian - 3/29/2025, 6:33 PM
Katherine Langford could be my Claire.
User Comment Image
Taonrey
Taonrey - 3/29/2025, 9:38 PM
@Repian - she kinda a bad actor but I doubt these movies are going to need great performances so I’m down for this casting
Urubrodi
Urubrodi - 3/30/2025, 6:33 PM
@Repian - Yeah I can see that, reminds of the character model from the more recent remakes.
TheLobster
TheLobster - 3/29/2025, 6:39 PM
After her winning an Oscar? Fat chance lmao
Nonameforme
Nonameforme - 3/29/2025, 6:54 PM
Eh... no thanks
LeonNova
LeonNova - 3/29/2025, 7:02 PM
She gives me more Claire than Jill, but I could see her pulling off either.
McMurdo
McMurdo - 3/29/2025, 7:06 PM
Yeah I'm sure she'll sign on /s
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