For months there have been rumors of Wesley Snipes meeting with Marvel about a role in the MCU, but news coming either has been sparce. In a recent video gathered TMZ, Snipes states that he has been in talks to do a Superhero movie. With Blade being back in the hands of Marvel, that was the initial thought for many. But without a Blade movie scheduled in the next few years, that does not seem likely. That does not mean Blade will not appear, only I do not think Snipes will play that role.
Once Blade appears, Marvel will want someone that can play the role for 10 to 15 years. With Snipes already at 53, I do not think they would want to put forth that risk as they are already doing that with Robert Downey Jr. Also if Snipes were to reprise the role, the question of continuity comes up. Did the Blade Trilogy happen in the shadows of the MCU? While possible, it would take creative writing and legal wrangling. I think this is highly likely to happen so they will not have to explain or do an origin movie for Blade, as Marvel has stated they are finished with origins.
But again I do not feel that Snipes wll be Blade, if he shows up in the MCU. I believe he will most likely appear as King T'Chaka, father of the Black Panther T'Challa. During the popularity of the first two Blade movies, Snipes intended to make a Black Panther movie. These talks go back to 1993, years before The first Blade movie. So he has some vested interest in participating in the movie I am sure. Though he is older, he does not look so old as he could not appear in flashbacks and require CG. With Cage already cast, there are few characters (other than the Guardians movies and possibliy the Inhumans) that Snipes would fit so easily into. But that's just my opinion.